Despite DNA N4-methylcytosine (4mC) was found in 1983, our current knowledge about its biological functions is very limited. In order to reveal its new functions, it is necessary to develop various methods to identify 4mC sites. Although experimental methods have been proposed to detect 4mC sites, they are expensive for performing genome-wide detections. Thus, it is necessary to develop computational methods for predicting 4mC sites. To this end, we developed iDNA4mC, the first webserver to identify 4mC sites in both prokaryotic and eukaryotic genomes. Caveat
(1) For each submission, the input sequences must be longer than 41 characters and in FASTA format; i.e., each DNA sequence should start with a greater-than symbol (" > ") in the first column. The words right after the " > " symbol in the single initial line are optional and only used for the purpose of identification and description. (2) If a query sequence contains any illegal characters, wrong results will be obtained. |