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Q9V3P0

UniProt ID :

Q9V3P0

NCBI Taxonomy :

7227

Protein names :

Peroxiredoxin 1

Organism :

Drosophila melanogaster

Taxonomy :

Eukaryota

Subcellular locations :

Cytoplasm;

Length :

194

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005829	Cellular Component	cytosol	IDA
GO:0005875	Cellular Component	microtubule associated complex	IDA
GO:0008379	Molecullar Function	thioredoxin peroxidase activity	IDA
GO:0007155	Biological Process	cell adhesion	IMP
GO:0045454	Biological Process	cell redox homeostasis	IDA
GO:0008340	Biological Process	determination of adult lifespan	IMP
GO:0007281	Biological Process	germ cell development	IMP
GO:0008354	Biological Process	germ cell migration	IMP
GO:0042744	Biological Process	hydrogen peroxide catabolic process	IDA
GO:0006974	Biological Process	response to DNA damage stimulus	IMP
GO:0042594	Biological Process	response to starvation	IMP

Catalytic activity :

2 R'-SH + ROOH = R'-S-S-R' + H₂O + ROH.

SWISS-MODEL Repository :

Q9V3P0

Sequences :

MPQLQKPAPAFAGTAVVNGVFKDIKLSDYKGKYLVLFFYPLDFTFVCPTEIIAFSESAAEFRKINCEVIGCSTDSQFTHLAWINTPRKQGGLGSMDIPLLADKSMKVARDYGVLDEETGIPFRGLFIIDDKQNLRQITVNDLPVGRSVEETLRLVQAFQYTDKYGEVCPANWKPGQKTMVADPTKSKEYFETTS

Function :

Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. As a reducing substrate, thioredoxin 2 is preferred over thioredoxin 1.