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Q9TSX9

UniProt ID :

Q9TSX9

NCBI Taxonomy :

9823

Protein names :

Peroxiredoxin-6

Organism :

Sus scrofa

Taxonomy :

Eukaryota

Subcellular locations :

Cytoplasm;Lysosome;Cytoplasmic vesicle;

Length :

224

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005737	Cellular Component	cytoplasm	ISS
GO:0016023	Cellular Component	cytoplasmic membrane-bounded vesicle	IEA
GO:0005764	Cellular Component	lysosome	IEA
GO:0004602	Molecullar Function	glutathione peroxidase activity	IEA
GO:0051920	Molecullar Function	peroxiredoxin activity	IEA
GO:0004623	Molecullar Function	phospholipase A2 activity	IEA
GO:0009395	Biological Process	phospholipid catabolic process	IEA
GO:0006979	Biological Process	response to oxidative stress	IEA

Catalytic activity :

2 R'-SH + ROOH = R'-S-S-R' + H₂O + ROH.2 glutathione + H₂O₂ = glutathione disulfide + 2 H₂O.

SWISS-MODEL Repository :

Q9TSX9

Sequences :

MPGGLLLGDEAPNFEANTTIGRIRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLAPEFAKRNVKMIALSIDSVEDHLAWSKDINAYNGEEPKETLPFPIIDDKSRDLAIQLGMLDPAEKDEQGMPVTARVVFIFGPDKKLKLSILYPATTGRNFDEILRVIISLQLTAEKRVATPVDWKNGDSVMVLPNIPEEEAKKLFPKGVFTKELPSGKKYLRYTPQP

Function :

Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury (By similarity).