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Q9FGS4

UniProt ID :

Q9FGS4

NCBI Taxonomy :

3702

Protein names :

Quinolinate synthase, chloroplastic

Organism :

Arabidopsis thaliana

Taxonomy :

Eukaryota

Subcellular locations :

Plastid;

Length :

718

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0009507	Cellular Component	chloroplast	IDA
GO:0051539	Molecullar Function	4 iron, 4 sulfur cluster binding	IDA
GO:0008047	Molecullar Function	enzyme activator activity	IDA
GO:0046872	Molecullar Function	metal ion binding	IEA
GO:0042803	Molecullar Function	protein homodimerization activity	IDA
GO:0008987	Molecullar Function	quinolinate synthetase A activity	IMP
GO:0016740	Molecullar Function	transferase activity	IEA
GO:0009060	Biological Process	aerobic respiration	IMP
GO:0016226	Biological Process	iron-sulfur cluster assembly	IC
GO:0009435	Biological Process	NAD biosynthetic process	IMP
GO:0051176	Biological Process	positive regulation of sulfur metabolic process	IDA
GO:0051347	Biological Process	positive regulation of transferase activity	IMP

Catalytic activity :

Glycerone phosphate + iminosuccinate = pyridine-2,3-dicarboxylate + 2 H₂O + phosphate.

SWISS-MODEL Repository :

Q9FGS4

Sequences :

MALALSVAPTSSSLSSLLSRTPNPSPNFRTTHLNFGSQRRIYTINPLLRSFKCLQSSSRDVNASPFSISAIASSSSSSQTTELVPYKLQRLVKEFKSLTEPIDRLKWVLHYASLLPQMPESSKTESNRVMGCTARVWLDAELGQDGKMRFCADSDSDVSKGMCSCLIQVLDEASPVEVMELKTEDLAELNVGLLGGERSRVNTWYNVLVSMQKKTRRLVAEREGKVPSFEPFPSLVLTAHGIEAKGSFAQAQAKYLFPEESRVEELVNVLKEKKIGVVAHFYMDPEVQGVLTAAQKHWPHISISDSLVMADSAVTMAKAGCQFITVLGVDFMSENVRAILDQAGFEKVGVYRMSDETIGCSLADAASAPAYLNYLEAASRSPPSLHVVYINTSLETKAFAHELVPTITCTSSNVVQTILQAFAQMPELTVWYGPDSYMGANIVKLFQQMTLMTNEEIANIHPKHSLDSIKSLLPRLHYFQEGTCIVHHLFGHEVVERIKYMYCDAFLTAHLEVPGEMFSLAMEAKKREMGVVGSTQNILDFIKQKVQEAVDRNVDDHLQFVLGTESGMVTSIVAVIRSLLGSSANSKLKVEVVFPVSSDSMTKTSSDSSNSIKVGDVALPVVPGVAGGEGCSIHGGCASCPYMKMNSLSSLLKVCHKLPDLENVYGGFIAERFKRQTPQGKLIADVGCEPILHMRHFQANKELPDKLVHQVLSCESKR

Function :

Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. Can complement nadA-deficient E.coli mutant. Participates also in cysteine desulfurization mediated by NFS2. Can activate the cysteine desulfurase activity of NFS2 in vitro.