show

Q99MH5

UniProt ID :

Q99MH5

NCBI Taxonomy :

10090

Protein names :

Nucleoside diphosphate kinase homolog 5

Organism :

Mus musculus

Taxonomy :

Eukaryota

Length :

211

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0036126	Cellular Component	sperm flagellum	IDA
GO:0005524	Molecullar Function	ATP binding	IEA
GO:0004550	Molecullar Function	nucleoside diphosphate kinase activity	IEA
GO:0042384	Biological Process	cilium assembly	IMP
GO:0006241	Biological Process	CTP biosynthetic process	IEA
GO:0003351	Biological Process	epithelial cilium movement	IMP
GO:0006183	Biological Process	GTP biosynthetic process	IEA
GO:1902176	Biological Process	negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress	IDA
GO:0000302	Biological Process	response to reactive oxygen species	NAS
GO:0007286	Biological Process	spermatid development	IDA
GO:0006228	Biological Process	UTP biosynthetic process	IEA
GO:0021591	Biological Process	ventricular system development	IMP

SWISS-MODEL Repository :

Q99MH5

Sequences :

MEVSMPLPQIYVEKTLALIKPDVVDKEEEIQDIILGSGFTIIQRRKLHLSPEHCSNFYVEQYGKMFFPNLTAYMSSGPLVAMILARHKAISYWKELMGPSNSLVAKETHPDSLRAIYGTDELRNALHGSNDFAASEREIRFMFPAVIIEPIPIGQAAKDYINLYVAPTLLQGLTELCKEKPPDPYLWLADWLMKNNPNKPKLCHFPVTEEP

Function :

Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species.