Q8T6C4
UniProt ID : Q8T6C4
NCBI Taxonomy : 6210
Protein names : Thioredoxin peroxidase
Organism : Echinococcus granulosus
Taxonomy : Eukaryota
Subcellular locations :Cytoplasm;
Length : 193
Gene Ontology :
GO IDOntologyDefinitionEvidence
GO:0005737Cellular ComponentcytoplasmIEA
GO:0004601Molecullar Functionperoxidase activityIEA
GO:0051920Molecullar Functionperoxiredoxin activityIEA
Catalytic activity :2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH.
SWISS-MODEL Repository :Q8T6C4
Sequences : MAAVVGKLAPSFTCKALVDGELKDVSLSDYRGKYVILFFYPMDFTFVCPTEIIAFNDRADEFHQRGCQLLACSTDSGYCHLAWNNVSRKEGGVQGMRIPMLADTNHKISRDYGVLIEDQGIALRGLFIIDDKGVLRQITINDLPVGRSVDEALRLLDAFQFTDKHGEVCPANWQPGSKTFKPSAGDLKSFMSS
Function :Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) (By similarity).