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Q8GY89

UniProt ID :

Q8GY89

NCBI Taxonomy :

3702

Protein names :

Sulfiredoxin, chloroplastic/mitochondrial

Organism :

Arabidopsis thaliana

Taxonomy :

Eukaryota

Subcellular locations :

Plastid;Mitochondrion;

Length :

125

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0009507	Cellular Component	chloroplast	IDA
GO:0005739	Cellular Component	mitochondrion	IDA
GO:0005524	Molecullar Function	ATP binding	IEA
GO:0003677	Molecullar Function	DNA binding	IEA
GO:0032542	Molecullar Function	sulfiredoxin activity	IEA

Catalytic activity :

Peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH = peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R.

SWISS-MODEL Repository :

Q8GY89

Sequences :

MANLMMRLPISLRSFSVSASSSNGSPPVIGGSSGGVGPMIVELPLEKIRRPLMRTRSNDQNKVKELMDSIRQIGLQVPIDVIEVDGTYYGFSGCHRYEAHQKLGLPTIRCKIRKGTKETLRHHLR

Function :

Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in a peroxiredoxin. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase. Required to switch on the antioxidant pathway to regenerate the oxidative damage. In mitochondrion, catalyzes the retroreduction of the inactive sulfinic form of atypical Prx IIF using thioredoxin as reducing agent.