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Q5RC63

UniProt ID :

Q5RC63

NCBI Taxonomy :

9601

Protein names :

Peroxiredoxin-2

Organism :

Pongo abelii

Taxonomy :

Eukaryota

Subcellular locations :

Cytoplasm;

Length :

177

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005737	Cellular Component	cytoplasm	IEA
GO:0004601	Molecullar Function	peroxidase activity	IEA
GO:0051920	Molecullar Function	peroxiredoxin activity	IEA

Catalytic activity :

2 R'-SH + ROOH = R'-S-S-R' + H₂O + ROH.

SWISS-MODEL Repository :

Q5RC63

Sequences :

MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDFHKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLKTDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEGPCFASP

Function :

Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) (By similarity).