Q5LS57
UniProt ID : Q5LS57
NCBI Taxonomy : 246200
Protein names : Dimethylsulfonioproprionate demethylase DmdA
Organism : Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)
Taxonomy : Bacteria
Length : 364
Gene Ontology :
GO IDOntologyDefinitionEvidence
GO:0005737Cellular ComponentcytoplasmIEA
GO:0004047Molecullar Functionaminomethyltransferase activityIEA
GO:0006546Biological Processglycine catabolic processIEA
Catalytic activity :S,S-dimethyl-beta-propiothetin + tetrahydrofolate = 3-(methylthio)propanoate + 5-methyltetrahydrofolate.
Sequences : MASIFPSRRVRRTPFSAGVEAAGVKGYTVYNHMLLPTVFDSLQADCAHLKEHVQVWDVACERQVSIQGPDALRLMKLISPRDMDRMADDQCYYVPTVDHRGGMLNDPVAVKLAADHYWLSLADGDLLQFGLGIAIARGFDVEIVEPDVSPLAVQGPRADDLMARVFGEAVRDIRFFRYKRLAFQGVELVVARSGWSKQGGFEIYVEGSELGMPLWNALFAAGADLNVRAGCPNNIERVESGLLSYGNDMTRENTPYECGLGKFCNSPEDYIGKAALAEQAKNGPARQIRALVIGGEIPPCQDAWPLLADGRQVGQVGSAIHSPEFGVNVAIGMVDRSHWAPGTGMEVETPDGMRPVTVREGFWR
Function :Major contributor to the demethylation of dimethlysulfonioproprionate (DMSP). Demethylates DMSP to methyl-mercaptopropionate (MMPA). The intracellular concentration of DMSP is estimated to be 70 mM.