Q5LS57 |
UniProt ID : |
Q5LS57 |
NCBI Taxonomy : |
246200 |
Protein names : |
Dimethylsulfonioproprionate demethylase DmdA |
Organism : |
Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) |
Taxonomy : |
Bacteria |
Length : |
364 |
Gene Ontology : | GO ID | Ontology | Definition | Evidence | GO:0005737 | Cellular Component | cytoplasm | IEA | GO:0004047 | Molecullar Function | aminomethyltransferase activity | IEA | GO:0006546 | Biological Process | glycine catabolic process | IEA | |
Catalytic activity : | S,S-dimethyl-beta-propiothetin + tetrahydrofolate = 3-(methylthio)propanoate + 5-methyltetrahydrofolate. |
Sequences : |
MASIFPSRRVRRTPFSAGVEAAGVKGYTVYNHMLLPTVFDSLQADCAHLKEHVQVWDVACERQVSIQGPDALRLMKLISPRDMDRMADDQCYYVPTVDHRGGMLNDPVAVKLAADHYWLSLADGDLLQFGLGIAIARGFDVEIVEPDVSPLAVQGPRADDLMARVFGEAVRDIRFFRYKRLAFQGVELVVARSGWSKQGGFEIYVEGSELGMPLWNALFAAGADLNVRAGCPNNIERVESGLLSYGNDMTRENTPYECGLGKFCNSPEDYIGKAALAEQAKNGPARQIRALVIGGEIPPCQDAWPLLADGRQVGQVGSAIHSPEFGVNVAIGMVDRSHWAPGTGMEVETPDGMRPVTVREGFWR |
Function : | Major contributor to the demethylation of dimethlysulfonioproprionate (DMSP). Demethylates DMSP to methyl-mercaptopropionate (MMPA). The intracellular concentration of DMSP is estimated to be 70 mM. |