Q500Y9
UniProt ID : Q500Y9
NCBI Taxonomy : 3702
Protein names : NADH kinase
Organism : Arabidopsis thaliana
Taxonomy : Eukaryota
Subcellular locations :Cytoplasm;
Length : 317
Gene Ontology :
GO IDOntologyDefinitionEvidence
GO:0005829Cellular ComponentcytosolIDA
GO:0005524Molecullar FunctionATP bindingIEA
GO:0003951Molecullar FunctionNAD+ kinase activityIDA
GO:0042736Molecullar FunctionNADH kinase activityIDA
GO:0019674Biological ProcessNAD metabolic processIEA
GO:0006741Biological ProcessNADP biosynthetic processIMP
Catalytic activity :ATP + NADH = ADP + NADPH.
SWISS-MODEL Repository :Q500Y9
Sequences : MAIRKLLLLLKPIDPYPFLQTEGASLIKNPQVLQYLESRCKVHKNAIKFCQEILSKKPVEWKPISRNDLSHPIRDVDMVITVGGDGTLLHASHFIDDSVPVLGVNSDPTQAHEVEELSDQFDASRSTGHLCAATVENFEQVLDDILFGRVVPAKVSRISLKLNSETLLSHALNDILIAQPCPAAVSRFSFKIKNKDGASSPKTVNCRSSGLRICTAAGSTAAMQSAGGFVMPMLSRDLQFMVREPISPGSTASLMHSTFKPDQFMDVNWYSDHGTIYIDGCQVQHSVQLGDTIEISSDAPVLNVFLSHGISQIRSRY
Function :Phosphorylates specifically NADH. Can phosphorylate NAD with a 100-fold decrease in efficiency compared to NADH. Prefers ATP as nucleoside triphosphate substrate. Can also utilize UTP, GTP and CTP. Key source of the cellular reductant NADPH which is an important antioxidant factor.