Q3KTM2
UniProt ID : Q3KTM2
NCBI Taxonomy : 9031
Protein names : Glycerophosphodiester phosphodiesterase domain-containing protein 5
Organism : Gallus gallus
Taxonomy : Eukaryota
Subcellular locations :Endomembrane system;Cytoplasm;Cell projection;
Length : 599
Gene Ontology :
GO IDOntologyDefinitionEvidence
GO:0012505Cellular Componentendomembrane systemIEA
GO:0030426Cellular Componentgrowth coneIEA
GO:0016021Cellular Componentintegral to membraneIEA
GO:0048471Cellular Componentperinuclear region of cytoplasmIEA
GO:0008889Molecullar Functionglycerophosphodiester phosphodiesterase activityIMP
GO:0006071Biological Processglycerol metabolic processIEA
GO:0006629Biological Processlipid metabolic processIEA
GO:0045746Biological Processnegative regulation of Notch signaling pathwayIGI
GO:0007399Biological Processnervous system developmentIEA
Sequences : MVKHQPLQYYEPQLCLSCLTGIYGCRWKRYQRSHDDTTKWERLWFLILTSSFFLTLVWFYFWWEVHNDYNEINWFLYNRMGYWSDWSIPILVTTAAGFTYITVLLILALCHIAVGQQMNLHWLHKIGLMTTLITTVVTMSSIAQLWDDEWEMVFISLQATAPFLHIGALAAVTALSWLIAGQFARMEKATSQMLMVTAYLAVVVALYLVPLTISSPCIMEKKALGPKPAIIGHRGAPMLAPENTLMSFQKAVEQKIYGVQADVILSYDGVPFLMHDKTLRRTTNVEEVFPGRAYEHSSMFNWTDLEMLNAGEWFLRNDPFWTAGSLSRSDYLEAANQSVCKLADMLEVIKDNTSLILNFQDLPPDHPYYTSYINITLKTILASGIQQQAVMWLPDTERQLVRQIAPAFQQTSGLKLDAERLREKGIVKLNLRYTKVTNEDVRDYMAANLSVNLYTVNEPWLYSILWCTGVPSVTSDSSHVLRKVPFPIWLMPPDEYRLIWITSDLISFIIIVGVFIFQNYHNDQWRLGSIRTYNPEQIMLSAAVRRSSRDVKIMKEKLIFSEINNGVETTDELSLCSENGYANEMVTPTDHRDTRLRMN
Function :Promotes cell cycle exit and drives spinal motor neuron differentiation. The glycerophosphodiester phosphodiesterase activity may be required for its role in neuronal differentiation.