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Q06892

UniProt ID :

Q06892

NCBI Taxonomy :

559292

Protein names :

NADH kinase POS5, mitochondrial

Organism :

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Taxonomy :

Eukaryota

Subcellular locations :

Mitochondrion matrix;

Length :

414

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005759	Cellular Component	mitochondrial matrix	IDA
GO:0005524	Molecullar Function	ATP binding	IEA
GO:0003951	Molecullar Function	NAD+ kinase activity	IEA
GO:0042736	Molecullar Function	NADH kinase activity	IDA
GO:0034599	Biological Process	cellular response to oxidative stress	IMP
GO:0019674	Biological Process	NAD metabolic process	IEA
GO:0006741	Biological Process	NADP biosynthetic process	IDA

Catalytic activity :

ATP + NADH = ADP + NADPH.

SWISS-MODEL Repository :

Q06892

Sequences :

MFVRVKLNKPVKWYRFYSTLDSHSLKLQSGSKFVKIKPVNNLRSSSSADFVSPPNSKLQSLIWQNPLQNVYITKKPWTPSTREAMVEFITHLHESYPEVNVIVQPDVAEEISQDFKSPLENDPNRPHILYTGPEQDIVNRTDLLVTLGGDGTILHGVSMFGNTQVPPVLAFALGTLGFLSPFDFKEHKKVFQEVISSRAKCLHRTRLECHLKKKDSNSSIVTHAMNDIFLHRGNSPHLTNLDIFIDGEFLTRTTADGVALATPTGSTAYSLSAGGSIVSPLVPAILMTPICPRSLSFRPLILPHSSHIRIKIGSKLNQKPVNSVVKLSVDGIPQQDLDVGDEIYVINEVGTIYIDGTQLPTTRKTENDFNNSKKPKRSGIYCVAKTENDWIRGINELLGFNSSFRLTKRQTDND

Function :

Phosphorylates both NADH and NAD(+), with a twofold preference for NADH. Anti-oxidant factor and key source of the cellular reductant NADPH.