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Q00637

UniProt ID :

Q00637

NCBI Taxonomy :

7227

Protein names :

Superoxide dismutase [Mn], mitochondrial

Organism :

Drosophila melanogaster

Taxonomy :

Eukaryota

Subcellular locations :

Mitochondrion matrix;

Length :

217

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005759	Cellular Component	mitochondrial matrix	IEA
GO:0016209	Molecullar Function	antioxidant activity	NAS
GO:0046872	Molecullar Function	metal ion binding	IEA
GO:0004784	Molecullar Function	superoxide dismutase activity	IEA
GO:0008340	Biological Process	determination of adult lifespan	IMP
GO:0035206	Biological Process	regulation of hemocyte proliferation	IMP
GO:0019222	Biological Process	regulation of metabolic process	IMP
GO:0006801	Biological Process	superoxide metabolic process	IEA

Catalytic activity :

2 superoxide + 2 H⁺ = O₂ + H₂O₂.

SWISS-MODEL Repository :

Q00637

Sequences :

MFVARKISPNCKPGVRGKHTLPKLPYDYAALEPIICREIMELHHQKHHQTYVNNLNAAEEQLEEAKSKSDTTKLIQLAPALRFNGGGHINHTIFWQNLSPNKTQPSDDLKKAIESQWKSLEEFKKELTTLTVAVQGSGWGWLGFNKKSGKLQLAALPNQDPLEASTGLIPLFGIDVWEHAYYLQYKNVRPSYVEAIWDIANWDDISCRFQEAKKLGC

Function :

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.