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P70195

UniProt ID :

P70195

NCBI Taxonomy :

10090

Protein names :

Proteasome subunit beta type-7

Organism :

Mus musculus

Taxonomy :

Eukaryota

Subcellular locations :

Cytoplasm;Nucleus;

Length :

277

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005829	Cellular Component	cytosol	TAS
GO:0005634	Cellular Component	nucleus	IEA
GO:0005839	Cellular Component	proteasome core complex	IDA
GO:0004298	Molecullar Function	threonine-type endopeptidase activity	IEA
GO:0051603	Biological Process	proteolysis involved in cellular protein catabolic process	IEA

Catalytic activity :

Cleavage of peptide bonds with very broad specificity.

SWISS-MODEL Repository :

P70195

Sequences :

MAAVSVFQPPVGGFSFDNCRRNAVLEADFAKKGFKLPKARKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLTTGRLPRVVTANRMLKQMLFRYQGYIGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAAGIFNDLGSGSNIDLCVISKSKLDFLRPFSVPNKKGTRLGRYRCEKGTTAVLTEKVTPLEIEVLEETVQTMDTS

Function :

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the trypsin-like activity of the proteasome (By similarity).