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P56597

UniProt ID :

P56597

NCBI Taxonomy :

9606

Protein names :

Nucleoside diphosphate kinase homolog 5

Organism :

Homo sapiens

Taxonomy :

Eukaryota

Length :

212

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0036126	Cellular Component	sperm flagellum	IEA
GO:0005524	Molecullar Function	ATP binding	IEA
GO:0004550	Molecullar Function	nucleoside diphosphate kinase activity	TAS
GO:0006241	Biological Process	CTP biosynthetic process	IEA
GO:0003351	Biological Process	epithelial cilium movement	IEA
GO:0006183	Biological Process	GTP biosynthetic process	IEA
GO:0043066	Biological Process	negative regulation of apoptotic process	IEA
GO:0009116	Biological Process	nucleoside metabolic process	TAS
GO:0007286	Biological Process	spermatid development	ISS
GO:0006228	Biological Process	UTP biosynthetic process	IEA
GO:0021591	Biological Process	ventricular system development	IEA

SWISS-MODEL Repository :

P56597

Sequences :

MEISMPPPQIYVEKTLAIIKPDIVDKEEEIQDIILRSGFTIVQRRKLRLSPEQCSNFYVEKYGKMFFPNLTAYMSSGPLVAMILARHKAISYWLELLGPNNSLVAKETHPDSLRAIYGTDDLRNALHGSNDFAAAEREIRFMFPEVIVEPIPIGQAAKDYLNLHIMPTLLEGLTELCKQKPADPLIWLADWLLKNNPNKPKLCHHPIVEEPY

Function :

Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species (By similarity).