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P41963

UniProt ID :

P41963

NCBI Taxonomy :

6280

Protein names :

Extracellular superoxide dismutase [Cu-Zn]

Organism :

Brugia pahangi

Taxonomy :

Eukaryota

Subcellular locations :

Secreted;

Length :

199

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005615	Cellular Component	extracellular space	IEA
GO:0046872	Molecullar Function	metal ion binding	IEA
GO:0004784	Molecullar Function	superoxide dismutase activity	IEA
GO:0006801	Biological Process	superoxide metabolic process	IEA

Catalytic activity :

2 superoxide + 2 H⁺ = O₂ + H₂O₂.

SWISS-MODEL Repository :

P41963

Sequences :

MMIASFAIFLSHIIFITYATSNQRYFKPNMHNNMTITIRRTITKTATAIAVLHSDNGNINGTIHFQQDKNSTTISGEIKGLTPGLHGFHVHQYGDTTNGCISAGPHFNPYNKTHGDPTDEMRHVGDLGNIVAGADGTAHIDISDKHVQLLGPNSIIGRSLVVHADQDDLGKGVGDKKDESLKTGNAGGRVACGIVAISA

Function :

Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen. May act in the parasite defense by neutralizing superoxide generated by activated leukocytes, thus acting as both an antioxidant and an anti-inflammatory factor.