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P36077

UniProt ID :

P36077

NCBI Taxonomy :

559292

Protein names :

Sulfiredoxin

Organism :

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Taxonomy :

Eukaryota

Subcellular locations :

Cytoplasm;Nucleus;

Length :

127

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005737	Cellular Component	cytoplasm	IEA
GO:0005634	Cellular Component	nucleus	IEA
GO:0005524	Molecullar Function	ATP binding	IEA
GO:0003677	Molecullar Function	DNA binding	IEA
GO:0032542	Molecullar Function	sulfiredoxin activity	IDA
GO:0034599	Biological Process	cellular response to oxidative stress	IMP

Catalytic activity :

Peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH = peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R.Magnesium.

SWISS-MODEL Repository :

P36077

Sequences :

MSLQSNSVKPTEIPLSEIRRPLAPVLDPQKIDAMVATMKGIPTASKTCSLEQAEAAASAGELPPVDVLGVRVKGQTLYYAFGGCHRLQAYDRRARETQNAAFPVRCRVLPATPRQIRMYLGSSLDIE

Function :

Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxin TSA1. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and as thioltransferase.