P35705
UniProt ID : P35705
NCBI Taxonomy : 9913
Protein names : Thioredoxin-dependent peroxide reductase, mitochondrial
Organism : Bos taurus
Taxonomy : Eukaryota
Subcellular locations :Mitochondrion;
Length : 257
Gene Ontology :
GO IDOntologyDefinitionEvidence
GO:0005769Cellular Componentearly endosomeIEA
GO:0008385Cellular ComponentIkappaB kinase complexIEA
GO:0005739Cellular ComponentmitochondrionIEA
GO:0043027Molecullar Functioncysteine-type endopeptidase inhibitor activity involved in apoptotic processIEA
GO:0004601Molecullar Functionperoxidase activityIEA
GO:0051920Molecullar Functionperoxiredoxin activityIEA
GO:0042744Biological Processhydrogen peroxide catabolic processIEA
GO:0001893Biological Processmaternal placenta developmentIEA
GO:0007005Biological Processmitochondrion organizationIEA
GO:0030099Biological Processmyeloid cell differentiationIEA
GO:0043066Biological Processnegative regulation of apoptotic processIEA
GO:0033673Biological Processnegative regulation of kinase activityIEA
GO:0008284Biological Processpositive regulation of cell proliferationIEA
GO:0051092Biological Processpositive regulation of NF-kappaB transcription factor activityIEA
GO:0051881Biological Processregulation of mitochondrial membrane potentialIEA
GO:0032496Biological Processresponse to lipopolysaccharideIEA
Catalytic activity :2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH.
SWISS-MODEL Repository :P35705
Sequences : MAATAGRLFRASLIRHVSAIPWGISASAALRPAASRRMCLTNALWSGSDQAKFAFSTSSSYHAPAVTQHAPYFKGTAVVSGEFKEISLDDFKGKYLVLFFYPLDFTFVCPTEIIAFSDKASEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGPGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQFVEAHGEVCPANWTPESPTIKPHPTASREYFEKVNQ
Function :Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical-generating system.