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P34760

UniProt ID :

P34760

NCBI Taxonomy :

559292

Protein names :

Peroxiredoxin TSA1

Organism :

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Taxonomy :

Eukaryota

Subcellular locations :

Cytoplasm;

Length :

196

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005829	Cellular Component	cytosol	IDA
GO:0005844	Cellular Component	polysome	IDA
GO:0043022	Molecullar Function	ribosome binding	IDA
GO:0008379	Molecullar Function	thioredoxin peroxidase activity	IDA
GO:0051082	Molecullar Function	unfolded protein binding	IMP
GO:0045454	Biological Process	cell redox homeostasis	IDA
GO:0034599	Biological Process	cellular response to oxidative stress	IDA
GO:0000077	Biological Process	DNA damage checkpoint	IGI
GO:0042262	Biological Process	DNA protection	IMP
GO:0006457	Biological Process	protein folding	IMP
GO:0001302	Biological Process	replicative cell aging	IMP
GO:0033194	Biological Process	response to hydroperoxide	IMP

Catalytic activity :

2 R'-SH + ROOH = R'-S-S-R' + H₂O + ROH.

SWISS-MODEL Repository :

P34760

Sequences :

MVAQVQKQAPTFKKTAVVDGVFDEVSLDKYKGKYVVLAFIPLAFTFVCPTEIIAFSEAAKKFEEQGAQVLFASTDSEYSLLAWTNIPRKEGGLGPINIPLLADTNHSLSRDYGVLIEEEGVALRGLFIIDPKGVIRHITINDLPVGRNVDEALRLVEAFQWTDKNGTVLPCNWTPGAATIKPTVEDSKEYFEAANK

Function :

Physiologically important antioxidant which constitutes an enzymatic defense against sulfur-containing radicals. Can provide protection against a thiol-containing oxidation system but not against an oxidation system without thiol.