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P0A5N4

UniProt ID :

P0A5N4

NCBI Taxonomy :

1773

Protein names :

Alkyl hydroperoxide reductase AhpD

Organism :

Mycobacterium tuberculosis

Taxonomy :

Bacteria

Length :

177

Gene Ontology :

GO ID	Ontology	Definition	Evidence
GO:0005829	Cellular Component	cytosol	TAS
GO:0005886	Cellular Component	plasma membrane	IDA
GO:0008785	Molecullar Function	alkyl hydroperoxide reductase activity	IEA
GO:0015036	Molecullar Function	disulfide oxidoreductase activity	IDA
GO:0032843	Molecullar Function	hydroperoxide reductase activity	IDA
GO:0004601	Molecullar Function	peroxidase activity	IEA
GO:0051920	Molecullar Function	peroxiredoxin activity	IEA
GO:0045454	Biological Process	cell redox homeostasis	IPI
GO:0070207	Biological Process	protein homotrimerization	IPI
GO:0052572	Biological Process	response to host immune response	TAS
GO:0006979	Biological Process	response to oxidative stress	IEA

Catalytic activity :

2 R'-SH + ROOH = R'-S-S-R' + H₂O + ROH.

SWISS-MODEL Repository :

P0A5N4

Sequences :

MSIEKLKAALPEYAKDIKLNLSSITRSSVLDQEQLWGTLLASAAATRNPQVLADIGAEATDHLSAAARHAALGAAAIMGMNNVFYRGRGFLEGRYDDLRPGLRMNIIANPGIPKANFELWSFAVSAINGCSHCLVAHEHTLRTVGVDREAIFEALKAAAIVSGVAQALATIEALSPS

Function :

Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.