P08228
UniProt ID : P08228
NCBI Taxonomy : 10090
Protein names : Superoxide dismutase [Cu-Zn]
Organism : Mus musculus
Taxonomy : Eukaryota
Subcellular locations :Cytoplasm;
Length : 154
Gene Ontology :
GO IDOntologyDefinitionEvidence
GO:0031410Cellular Componentcytoplasmic vesicleISS
GO:0005829Cellular ComponentcytosolISS
GO:0032839Cellular Componentdendrite cytoplasmISS
GO:0031012Cellular Componentextracellular matrixISS
GO:0005615Cellular Componentextracellular spaceISS
GO:0005739Cellular ComponentmitochondrionISS
GO:0043025Cellular Componentneuronal cell bodyISS
GO:0005634Cellular ComponentnucleusISS
GO:0005777Cellular ComponentperoxisomeIEA
GO:0005886Cellular Componentplasma membraneIEA
GO:0043234Cellular Componentprotein complexISS
GO:0051087Molecullar Functionchaperone bindingISS
GO:0005507Molecullar Functioncopper ion bindingISS
GO:0030346Molecullar Functionprotein phosphatase 2B bindingISS
GO:0004784Molecullar Functionsuperoxide dismutase activityIDA
GO:0008270Molecullar Functionzinc ion bindingISS
GO:0000187Biological Processactivation of MAPK activityIDA
GO:0007568Biological ProcessagingIMP
GO:0008089Biological Processanterograde axon cargo transportIMP
GO:0060088Biological Processauditory receptor cell stereocilium organizationIMP
GO:0007569Biological Processcell agingIEA
GO:0006879Biological Processcellular iron ion homeostasisIMP
GO:0007566Biological Processembryo implantationIMP
GO:0006749Biological Processglutathione metabolic processIMP
GO:0060047Biological Processheart contractionIMP
GO:0050665Biological Processhydrogen peroxide biosynthetic processIMP
GO:0007626Biological Processlocomotory behaviorIMP
GO:0046716Biological Processmuscle cell cellular homeostasisIMP
GO:0002262Biological Processmyeloid cell homeostasisIMP
GO:0045541Biological Processnegative regulation of cholesterol biosynthetic processISS
GO:0043524Biological Processnegative regulation of neuron apoptotic processIMP
GO:0060052Biological Processneurofilament cytoskeleton organizationIMP
GO:0001541Biological Processovarian follicle developmentIMP
GO:0032287Biological Processperipheral nervous system myelin maintenanceIMP
GO:0001819Biological Processpositive regulation of cytokine productionISS
GO:1902177Biological Processpositive regulation of intrinsic apoptotic signaling pathway in response to oxidative stressIEA
GO:0032930Biological Processpositive regulation of superoxide anion generationIEA
GO:0008217Biological Processregulation of blood pressureIMP
GO:0051881Biological Processregulation of mitochondrial membrane potentialISS
GO:0040014Biological Processregulation of multicellular organism growthIMP
GO:0032314Biological Processregulation of Rac GTPase activityIEA
GO:0060087Biological Processrelaxation of vascular smooth muscleIMP
GO:0019430Biological Processremoval of superoxide radicalsIMP
GO:0001975Biological Processresponse to amphetamineIEA
GO:0048678Biological Processresponse to axon injuryIMP
GO:0046688Biological Processresponse to copper ionIEA
GO:0042493Biological Processresponse to drugIMP
GO:0045471Biological Processresponse to ethanolIMP
GO:0009408Biological Processresponse to heatIMP
GO:0042542Biological Processresponse to hydrogen peroxideIMP
GO:0031667Biological Processresponse to nutrient levelsIEA
GO:0001895Biological Processretina homeostasisIMP
GO:0008090Biological Processretrograde axon cargo transportIMP
GO:0007605Biological Processsensory perception of soundIMP
GO:0007283Biological ProcessspermatogenesisIMP
GO:0042554Biological Processsuperoxide anion generationIDA
Catalytic activity :2 superoxide + 2 H+ = O2 + H2O2.
SWISS-MODEL Repository :P08228
Sequences : MAMKAVCVLKGDGPVQGTIHFEQKASGEPVVLSGQITGLTEGQHGFHVHQYGDNTQGCTSAGPHFNPHSKKHGGPADEERHVGDLGNVTAGKDGVANVSIEDRVISLSGEHSIIGRTMVVHEKQDDLGKGGNEESTKTGNAGSRLACGVIGIAQ
Function :Destroys radicals which are normally produced within the cells and which are toxic to biological systems.