P00442
UniProt ID : P00442
NCBI Taxonomy : 9913
Protein names : Superoxide dismutase [Cu-Zn]
Organism : Bos taurus
Taxonomy : Eukaryota
Subcellular locations :Cytoplasm;
Length : 152
Gene Ontology :
GO IDOntologyDefinitionEvidence
GO:0031410Cellular Componentcytoplasmic vesicleISS
GO:0005829Cellular ComponentcytosolISS
GO:0032839Cellular Componentdendrite cytoplasmIDA
GO:0031012Cellular Componentextracellular matrixISS
GO:0005615Cellular Componentextracellular spaceISS
GO:0005739Cellular ComponentmitochondrionISS
GO:0043025Cellular Componentneuronal cell bodyIDA
GO:0005634Cellular ComponentnucleusISS
GO:0043234Cellular Componentprotein complexIDA
GO:0051087Molecullar Functionchaperone bindingISS
GO:0005507Molecullar Functioncopper ion bindingISS
GO:0030346Molecullar Functionprotein phosphatase 2B bindingISS
GO:0004784Molecullar Functionsuperoxide dismutase activityISS
GO:0004842Molecullar Functionubiquitin-protein ligase activityISS
GO:0008270Molecullar Functionzinc ion bindingIDA
GO:0000187Biological Processactivation of MAPK activityISS
GO:0006309Biological Processapoptotic DNA fragmentationISS
GO:0060088Biological Processauditory receptor cell stereocilium organizationISS
GO:0007569Biological Processcell agingISS
GO:0006879Biological Processcellular iron ion homeostasisISS
GO:0006302Biological Processdouble-strand break repairISS
GO:0007566Biological Processembryo implantationISS
GO:0006749Biological Processglutathione metabolic processISS
GO:0060047Biological Processheart contractionISS
GO:0050665Biological Processhydrogen peroxide biosynthetic processISS
GO:0044419Biological Processinterspecies interaction between organismsIDA
GO:0007626Biological Processlocomotory behaviorISS
GO:0046716Biological Processmuscle cell cellular homeostasisISS
GO:0002262Biological Processmyeloid cell homeostasisISS
GO:0045541Biological Processnegative regulation of cholesterol biosynthetic processISS
GO:0043524Biological Processnegative regulation of neuron apoptotic processISS
GO:0060052Biological Processneurofilament cytoskeleton organizationISS
GO:0001541Biological Processovarian follicle developmentISS
GO:0032287Biological Processperipheral nervous system myelin maintenanceISS
GO:0001819Biological Processpositive regulation of cytokine productionISS
GO:0051770Biological Processpositive regulation of nitric-oxide synthase biosynthetic processIDA
GO:0043161Biological Processproteasomal ubiquitin-dependent protein catabolic processISS
GO:0000209Biological Processprotein polyubiquitinationISS
GO:0008217Biological Processregulation of blood pressureISS
GO:0051881Biological Processregulation of mitochondrial membrane potentialIDA
GO:0040014Biological Processregulation of multicellular organism growthISS
GO:0060087Biological Processrelaxation of vascular smooth muscleISS
GO:0019430Biological Processremoval of superoxide radicalsISS
GO:0048678Biological Processresponse to axon injuryISS
GO:0042493Biological Processresponse to drugISS
GO:0045471Biological Processresponse to ethanolISS
GO:0009408Biological Processresponse to heatISS
GO:0042542Biological Processresponse to hydrogen peroxideISS
GO:0001895Biological Processretina homeostasisISS
GO:0007605Biological Processsensory perception of soundISS
GO:0007283Biological ProcessspermatogenesisISS
Catalytic activity :2 superoxide + 2 H+ = O2 + H2O2.
SWISS-MODEL Repository :P00442
Sequences : MATKAVCVLKGDGPVQGTIHFEAKGDTVVVTGSITGLTEGDHGFHVHQFGDNTQGCTSAGPHFNPLSKKHGGPKDEERHVGDLGNVTADKNGVAIVDIVDPLISLSGEYSIIGRTMVVHEKPDDLGRGGNEESTKTGNAGSRLACGVIGIAK
Function :Destroys radicals which are normally produced within the cells and which are toxic to biological systems.